Table 1.
Characteristics of the patient cohort studied, their tumors and pathology progression.
| Sortilin staining | EGFR/Sortilin staining | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Weak to moderate | High | Not determined | P value | Wek to moderate | High | P value | |||
| N = | 55 | 26 | 26 | 3 | 35 | 20 | |||
| Genre | female | 16 | 11 | 4 | 1 | 0.09667 | 9 | 7 | 0.8112 |
| male | 39 | 16 | 21 | 2 | 25 | 14 | |||
| Age | mean | 56.7 yrs | 0.7954 | 0.2044 | |||||
| >/= 60 years | 22 | 12 | 9 | 1 | 14 | 8 | |||
| < 60 years | 33 | 14 | 17 | 2 | 21 | 12 | |||
| Tobacco | yes | 47 | 23 | 21 | 3 | 0.7007 | 27 | 20 | 0.2626 |
| no | 8 | 3 | 5 | 0 | 7 | 1 | |||
| Tumor | T1 | 2 | 2 | 0 | 0 | 0.4020 | 1 | 1 | 0.2648 |
| T2 | 21 | 10 | 11 | 0 | 11 | 10 | |||
| T3 | 17 | 8 | 6 | 3 | 14 | 3 | |||
| T4a | 15 | 6 | 9 | 0 | 9 | 6 | |||
| Stage | I | 2 | 2 | 0 | 0 | 0.2378 | 1 | 1 | 0.6071 |
| II | 7 | 2 | 5 | 0 | 4 | 3 | |||
| III | 12 | 5 | 4 | 3 | 10 | 2 | |||
| IVa | 32 | 17 | 15 | 0 | 19 | 13 | |||
| IVb | 2 | 0 | 2 | 0 | 1 | 1 | |||
| localization | oral cavity | 36 | 16 | 18 | 2 | 0.7707 | 22 | 14 | 0.8094 |
| oropharynx | 19 | 10 | 8 | 1 | 13 | 6 | |||
| Relapse | Total | 26 | 10 | 14 | 2 | 0.4040 | 20 | 6 | 0.09715 |
| T | 20 | 8 | 11 | 1 | 0.5646 | 14 | 6 | 0.6525 | |
| N | 11 | 4 | 7 | 0 | 0.4971 | 8 | 3 | 0.7261 | |
| M | 5 | 3 | 1 | 1 | 0.6594 | 4 | 1 | 0.6929 | |
| PNI positive | 22 | 13 | 7 | 2 | 0.1541 | 14 | 8 | 1 | |
| vascular emboli positive | 18 | 7 | 9 | 2 | 0.7638 | 13 | 5 | 0.5323 | |
| Lymph node positive | 29 | 17 | 11 | 1 | 0.1643 | 15 | 14 | 0.1715 | |
| capsular rupture | 22 | 12 | 9 | 1 | 0.5719 | 14 | 8 | 1 | |
Patient and tumor characteristics were compared between subgroups using Chi-square tests (chisq.test) for discrete qualitative or quantitative variables, and Student’s t-tests (t.test) for quantitative variables, applying a first-species risk α of 5%.