Table 3.
Antibiotic susceptibility pattern of S. aureus strains (case) isolated from patients with SCD (HbSS) (N = 47) compared with S. aureus strains (control) isolated from individuals without SCD disease (N = 16).
| Antibiotic | Group | Sensitive (N, %) |
Resistance (N, %) | p Values * |
|---|---|---|---|---|
| Amox | Case 1 | 13 (27.7) | 34 (72.3) | 0.001 |
| Control 2 | 12 (75) | 4 (25) | ||
| Amp | Case | 0 (0.0) | 47 (100) | 0.000 |
| Control | 0 (0.0) | 16 (100) | ||
| Azith | Case | 38 (80.9) | 9 (19.1) | 0.545 |
| Control | 14 (87.5) | 2 (12.5) | ||
| Cefaz | Case | 15 (31.9) | 32 (68.1) | 0.031 |
| Control | 10 (62.5) | 6 (37.5) | ||
| Cipro | Case | 39 (83) | 8 (17) | 0.669 |
| Control | 14 (87.5) | 2 (12.5) | ||
| Clinda | Case | 42 (89.9) | 5 (4.3) | 0.838 |
| Control | 14 (87.5) | 2 (12.5) | ||
| Dapto | Case | 47 (100) | 0 (0) | 0.000 |
| Control | 16 (100) | 0 (0) | ||
| Eryth | Case | 30 (63.8) | 17 (36.2) | 0.196 |
| Control | 13 (81.3) | 3 (18.8) | ||
| Fosfo | Case | 47 (100) | 0 (0) | 0.000 |
| Control | 16 (100) | 0 (0) | ||
| Fusa | Case | 39 (83) | 4 (8.9) | 0.869 |
| Control | 13 (81.3) | 2 (12.5) | ||
| Gent | Case | 47 (100) | 0 (0) | 0.084 |
| Control | 15 (93.8) | 1 (6.3) | ||
| Imi | Case | 15 (31.9) | 32 (68.1) | 0.003 |
| Control | 12 (75) | 4 (25) | ||
| Levo | Case | 42 (89.4) | 5 (10.6) | 0.4 |
| Control | 13 (81.3) | 3 (18.7) | ||
| Lzd | Case | 47 (100) | 0 | 0.000 |
| Control | 16 (100) | 0 | ||
| Moxi | Case | 40 (85.1) | 7 (14.9) | 0.358 |
| Control | 12 (75) | 4 (25) | ||
| Mup | Case | 47 (1000) | 0 (0) | 0.000 |
| Control | 16 (100) | 0 (0) | ||
| Ox | Case | 16 (34) | 31 (66) | 0.004 |
| Control | 12 (75) | 4 (25) | ||
| Pen | Case | 1 (2.1) | 46 (97.9) | 0.556 |
| Control | 0 (0) | 16 (100) | ||
| Rif | Case | 24 (51.1) | 2 (4.3) | 0.010 |
| Control | 15 (93.8) | 0 (0) | ||
| SXT | Case | 45 (95.7) | 2 (4.3) | 0.746 |
| Control | 15 (93.8) | 1 (6.3) | ||
| Synercid | Case | 47 (100) | 0 (0) | 0.000 |
| Control | 16 (100) | 0 (0) | ||
| Teico | Case | 47 (100) | 0 (0) | 0.000 |
| Control | 16 (100) | 0 (0) | ||
| Tetra | Case | 36 (76.6) | 11 (23.4) | 0.35 |
| Control | 14 (87.5) | 2 (12.5) | ||
| Tgc | Case | 47 (100) | 0 (0) | 0.000 |
| Control | 16 (100) | 0 (0) | ||
| Tobra | Case | 42 (89.4) | 5 (10.6) | 0.606 |
| Control | 15 (93.8) | 1 (6.3) | ||
| Vanc | Case | 44 (93.6) | 3 (6.4) | 0.434 |
| Control | 14 (87.5) | 2 (12.5) |
* The resistance rates of antibiotics among S. aureus compared with the sensitivity of those antibiotics among patients and control. 1 Case: 47 strains of S. aureus were isolated from patients with SCD (HbSS). 2 Control: 16 strains of S. aureus without the SCD disease.