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. 2017 Jun 13;39(7):322–329. doi: 10.1055/s-0037-1603744

Table 1. Psychometric properties of the screening tests.

Cut-off point Sensitivity and specificity for alcohol use disorder Predictive values
Positive result Negative result
Sensitivity
(95%CI)
Specificity
(95%CI)
True
(95%CI)
False
(95%CI)
True
(95%CI)
False
(95%CI)
AUDIT 4 0.87
(0.74-0.94)
0.86
(0.83-0.89)
0.36
(0.28-0.45)
0.64
(0.55-0.72)
0.99
(0.97-0.99)
0.01
(0.00-0.03)
AUDIT-C 3 0.90
(0.78-0.96)
0.79
(0.76-0.82)
0.28
(0.21-0.35)
0.72
(0.65-0.79)
0.99
(0.97-0.99)
0.01
(0.00-0.03)
TWEAK 2 0.96
(0.86-0.99)
0.77
(0.73-0.80)
0.27
(0.21-0.34)
0.73
(0.66-0.79)
0.99
(0.98-0.99)
0.01
(0.00-0.02)
RAPS-QF 1 0.79
(0.65-0.88)
0.82
(00.79-.85)
0.28
(0.21-0.36)
0.72
(0.64-0.79)
0.98
(0.96-0.99)
0.02
(0.01-0.04)
T-ACE 2 0.96
(0.86-0.99)
0.76
(0.72-0.79)
0.26
(0.20-0.33)
0.74
(0.67-0.80)
0.99
(0.98-0.99)
0.01
(0.00-0.02)
Likelihood Ratio M (SD) Reliability
(95%CI)
Cut-off point reliabilityc Correlation with the AUDITd
Positive (95%CI) Negative (95%CI)
AUDIT 6.37 (5.06–8.02) 0.16 (0.08-0.31) 2.30 (2.85) 0.76 (73–79)a 0.82
AUDIT-C 4.36 (3.63–5.22) 0.12 (0.05-0.28) 1.95 (1.92) 0.76 (73–79)a 0.81 0.93**
TWEAK 4.13 (3.53–4.83) 0.05 (0.01-0.20) 0.82 (1.38) 0.49 (42–55)b 0.70 0.79**
RAPS-QF 4.38 (3.51–5.47) 0.26 (0.15-0.44) 0.35 (0.74) 0.56 (0.50-.61)b 0.75 0.75**
T-ACE 3.98 (3.42–4.65) 0.05 (0.01-0.20) 0.72 (1.13) 0.33 (24–41)b 0.71 0.60**

Abbreviations: 95%CI, 95% confidence interval; AUDIT, Alcohol Use Disorder Identification Test; AUDIT-C, Alcohol Use Disorder Identification Test – Consumption; M, mean; SD, standard deviation; RAPS-QF, Rapid Alcohol Problems Screen – Quantity Frequency; T-ACE, Tolerance, Annoyed, Cut-Down and Eye-Opener; TWEAK, Tolerance, Worried, Eye-Opener, Amnesia and Cut-Down.

Notes: aCronbach's Alpha. bKuder-Richardson Formula 20 index. cLivingston's K2 coefficient. dAlcohol Use Disorders Identification Test. ** Significant at 0.01 (two-tailed).