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. 2023 Aug 9;94:416–425. doi: 10.2340/17453674.2023.17737

Table 8.

Overview of ALBC used in primary TKA with OA (N = 2,053,128) as reported by 15 of the 16 participating registries (except AJRR) from 2010–2020

Type/name of ALBC Company Viscosity Antibiotics used Used in TKA n (% of N)a
Palacos R + G Heraeus High Gentamicin 1,265,765 (62)
Refobacin Bonecemet R Zimmer Biomet High Gentamicin 362,845 (18)
Simplex with Tobramycin » Medium/high Tobramycin 101,001 (5.0)
CMW 2 G » Medium Gentamicin 90,927 (4.4)
Palacos MV+G » Medium Gentamicin 55,624 (2.7)
SmartSet GHV » High Gentamicin 58,331 (2.8)
CMW 1 G DePuy High Gentamicin 24,703 (1.2)
Copal G+ V or C+V » High Gentamicin and vancomycin or Clindamycin and vancomycin 10,116 (0.5)
Simplex HV » High Gentamicin 33,463 (1.6)
Cemex with Gentamicin Alere High Gentamicin 8,028 (0.4)
Palamed G » Medium Gentamicin 7,980 (0.4)
Refobacin Bonecemet R-3 » High Gentamicin 7,133 (0.4)
SmartSet GMV » Medium Gentamicin 5,015 (0.2)
Simplex EC Styrker Medium/high Erythromycin and colistin 4,419 (0.2)
Palacos (other than R + G) » Low/medium/high Vancomycin and gentamicin 4,477 (0.2)
Aminofix 1 Lépine Medium Gentamicin 2,796 (0.1)
Gentafix 1 Teknimed High Gentamicin 1,997 (0.1)
Hi-Fatigue G Bone Cement Zimmer High Gentamicin 1,073 (0.1)
Subiton G Subiton High Gentamicin 736 (0.0)
Versabond Smith & Nephew Medium Gentamicin 498 (0.0)
Smartset GMV Endurance » Medium Gentamicin 376 (0.0)
CMW 3 G » Low Gentamicin 352 (0.0)
Orthocem 1G » Standard/high Gentamicin 356 (0.0)
Synicem 1G MedicalExpo Standard Gentamicin 331 (0.0)
Rally HV » High Gentamicin 293 (0.0)
Refobacin Revision (Refobacin Revision-3) » High Gentamicin and clindamycin 274 (0.0)
Palacos LV+G » Low Gentamicin 164 (0.0)
Aminofix 3 » Low Gentamicin 103 (0.0)
Gentafix 3 » Low Gentamicin 94 (0.0)
Amplifix 1 Amplitude Medium Gentamicin 89 (0.0)
Genta C~ment 1 Bone Cement Biomedical High Gentamicin 85 (0.0)
Subiton Quirurgico G » Low Gentamicin 42 (0.0)
Biogent I » Standard Gentamicin 31 (0.0)
VancoGenx » High Vancomycin and gentamicin 19 (0.0)
MectaCem III Medacta Low/standard Gentamicin 14 (0.0)
Cemex Gent LV » Low Gentamicin 1 (0.0)
BonOs R Genta Osartis High Gentamicin 1 (0.0)
Other (not specified)b 1,216 (0.1)
Unknownc 2,360 (0.1)
a

FAR and KP reported a greater number of ALBC than the number of TKAs included. This was because patients may have had more than 1 type of cement, as explained by the KP. Thus, the total denominator of ALBC (n = 2,022,371) was greater than the number of TKA with ALBC included (n = 2,020,823) (see Table 2).

b

Procedure using a mixture of different types of cement or others. Difficult to differentiate antibiotics used because it is mixed-use and will contain cement with different antibiotics. Most of the antibiotics used are gentamicin (though a small number are mixed with erythromycin, tobramycin and/or vancomycin) but insufficient information in most procedures.

c

TKA with ALBC, but missing information on name of ALBC, antibiotic loaded, and /or company/manufacturer