Table 3.
The association between hyperuricemia and nephrolithiasis based on the multivariate binary logistic regression
| Covariate | OR (95%CI) | |||
|---|---|---|---|---|
| Model 1 | Model 2 | Model 3 | Model 4 | |
| Hyperuricemia | ||||
| No | Ref | Ref | Ref | Ref |
| Yes | 1.592(1.436,1.764)*** | 1.555(1.398,1.730)*** | 1.559(1.401,1.735)*** | 1.464(1.312,1.633)*** |
| Sex | ||||
| Male | Ref | Ref | Ref | |
| Female | 0.648(0.595,0.705)*** | 0.611(0.554,0.674)*** | 0.614(0.557,0.678)*** | |
| Ethnic Groups | ||||
| Han nationality | Ref | Ref | Ref | |
| Yi nationality | 1.790(1.623,1.975)*** | 1.775(1.609,1.959)*** | 1.725(1.562,1.905)*** | |
| Bai nationality | 1.583(1.431,1.750)*** | 1.562(1.411,1.729)*** | 1.540(1.391,1.705)*** | |
| Drinking frequency | ||||
| Never | Ref | Ref | ||
| Occasionally | 1.006(0.894,1.132) | 1.018(0.904,1.146) | ||
| 1–2 days/week | 0.723(0.498,1.050) | 0.721(0.496,1.047) | ||
| 3–5 days/week | 1.020(0.717,1.449) | 1.008(0.708,1.433) | ||
| Everyday | 0.766(0.651,0.903)** | 0.760(0.645,0.896)** | ||
| Hypertension | ||||
| No | Ref | |||
| Yes | 1.207(1.107,1.316)*** | |||
| Hyperlipidemia | ||||
| No | Ref | |||
| Yes | 1.110(1.017,1.212)* | |||
Bolden numbers indicate statistical significance (*p < 0.05, **p < 0.01, ***p < 0.001)
Model 1: crude model (without adjustment)
Model 2: Model 1 adjusted for demographic features (i.e., age, sex, ethnic group, educational level)
Model 3: Model 2 adjusted for life behavior factors (i.e., smoking status, drinking frequency)
Model 4: Model 3 adjusted for metabolic-related indicators and diseases (i.e., BMI, fasting blood glucose, Scr, Urea, hypertension, diabetes, fatty liver, hyperlipidemia)