Table 1.
Baseline characteristics CAD patients stratified by different uACR group
| Characteristics | Overall | uACR < 10 mg/g | 10 ≤ uACR < 30 mg/g | uACR ≥ 30 mg/g | P value |
|---|---|---|---|---|---|
| 5,960 | 4,763 | 681 | 516 | ||
| Age, years | 62.8 (10.4) | 62.3 (10.3) | 64.2 (10.4) | 64.8 (10.8) | < 0.001 |
| Female | 1435 (24.1) | 1088 (22.8) | 180 (26.4) | 167 (32.4) | < 0.001 |
| Smoking history | 1379 (23.8) | 1132 (24.4) | 154 (23.2) | 93 (18.5) | 0.011 |
| Acute myocardial infarction | 958 (16.1) | 696 (14.6) | 141 (20.7) | 121 (23.4) | < 0.001 |
| Hypertension | 3639 (61.1) | 2774 (58.2) | 446 (65.5) | 419 (81.2) | < 0.001 |
| Type 2 diabetes mellitus | 1888 (31.7) | 1311 (27.5) | 276 (40.5) | 301 (58.3) | < 0.001 |
| Congestive heart failure | 768 (12.9) | 496 (10.4) | 140 (20.6) | 132 (25.6) | < 0.001 |
| Chronic kidney disease | 971 (16.3) | 565 (11.9) | 133 (19.5) | 273 (52.9) | < 0.001 |
| Atrial fibrillation | 256 (4.3) | 185 (3.9) | 41 (6.0) | 30 (5.8) | 0.008 |
| Stroke | 460 (7.7) | 340 (7.1) | 63 (9.3) | 57 (11.0) | 0.002 |
| Hyperlipemia | 4021 (67.5) | 3189 (67.0) | 454 (66.7) | 378 (73.3) | 0.013 |
| Anemia | 1941 (33.5) | 1399 (30.1) | 247 (37.5) | 295 (58.6) | < 0.001 |
| PCI | 4397 (73.8) | 3480 (73.1) | 509 (74.7) | 408 (79.1) | 0.011 |
| uACR, mg/g | 14.3 (48.5) | 2.0 (2.2) | 16.0 (5.3) | 125.9 (115.4) | < 0.001 |
| eGFR, mL/min/1.73m2 | 92.7 (46.8) | 95.0 (43.8) | 91.0 (48.0) | 74.3 (64.8) | < 0.001 |
| Hemoglobin, g/L | 133.2 (17.2) | 134.7 (15.9) | 132.2 (17.0) | 120.5 (23.4) | < 0.001 |
| LDLC, mmol/L | 2.8 (0.9) | 2.8 (0.9) | 2.9 (0.9) | 3.0 (1.1) | < 0.001 |
| HDLC, mmol/L | 1.0 (0.2) | 1.0 (0.2) | 1.0 (0.3) | 1.0 (0.3) | 0.200 |
| LVEF, n(%) | 58.8 (11.9) | 59.7 (11.3) | 56.6 (13.3) | 54.0 (13.5) | < 0.001 |
| HbA1c, n(%) | 6.5 (1.4) | 6.3 (1.3) | 6.7 (1.6) | 7.2 (1.8) | < 0.001 |
| ACEI/ARB | 3961 (66.9) | 3202 (67.5) | 450 (66.7) | 309 (61.3) | 0.019 |
| β-blocker | 4937 (83.4) | 3943 (83.1) | 577 (85.5) | 417 (82.7) | 0.282 |
| Statins | 5030 (84.9) | 4097 (86.4) | 523 (77.5) | 410 (81.3) | < 0.001 |
| Spironolactone | 682 (11.5) | 435 (9.2) | 109 (16.1) | 138 (27.4) | < 0.001 |
| Dual antiplatelet therapy | 4256 (71.9) | 3420 (72.1) | 457 (67.7) | 379 (75.2) | 0.013 |
Values are mean ± SD, n (%), or median (IQR).
PCI: percutaneous coronary intervention; uACR: urine albumin creatinine ratio; eGFR: estimated glomerular filtration rate; LDLC: low density lipoprotein cholesterol; HDLC: high density lipoprotein cholesterol; HbAlc: glycosylated hemoglobin; ACEI: angiotensin-converting enzyme inhibitors; ARB: angiotensin receptor blockers