Table 1.
The Baseline Characteristics of Participants
| AIP | Q1(≤-0.299) | Q2(-0.299 to ≤-0.111) | Q3(-0.111 to ≤ 0.098) | Q4(> 0.098) | P-value |
|---|---|---|---|---|---|
| Participants | 25,017 | 25,016 | 25,016 | 25,020 | |
| Gender | < 0.001 | ||||
| Male | 6457 (25.81%) | 11,221 (44.86%) | 15,112 (60.41%) | 19,101 (76.34%) | |
| Female | 18,560 (74.19%) | 13,795 (55.14%) | 9904 (39.59%) | 5919 (23.66%) | |
| Age(years) | 39.46 ± 10.92 | 41.97 ± 12.34 | 44.26 ± 12.90 | 45.91 ± 12.61 | < 0.001 |
| Drinking status | |||||
| Current-drinker | 63 (0.25%) | 116 (0.46%) | 187 (0.75%) | 272 (1.09%) | |
| Ex- drinker | 595 (2.38%) | 1005 (4.02%) | 1245 (4.98%) | 1688 (6.75%) | |
| Never- drinker | 5158 (20.62%) | 5416 (21.65%) | 5669 (22.66%) | 6131 (24.50%) | |
| Not recorded | 19,201 (76.75%) | 18,479 (73.87%) | 17,915 (71.61%) | 16,929 (67.66%) | |
| Smoking status | < 0.001 | ||||
| Current-smoker | 454 (7.81%) | 920 (14.07%) | 1483 (20.88%) | 2451 (30.29%) | |
| Ex-smoker | 110 (1.89%) | 224 (3.43%) | 338 (4.76%) | 411 (5.08%) | |
| Never-smoker | 5252 (20.99%) | 5393 (21.56%) | 5280 (21.11%) | 5229 (20.90%) | |
| Not recorded | 19,201 (76.75%) | 18,479 (73.87%) | 17,915 (71.61%) | 16,929 (67.66%) | |
| Family history of diabetes | 0.882 | ||||
| No | 24,480 (97.85%) | 24,466 (97.80%) | 24,471 (97.82%) | 24,457 (97.75%) | |
| Yes | 537 (2.15%) | 550 (2.20%) | 545 (2.18%) | 563 (2.25%) | |
| SBP (mmHg) | 112.37 ± 14.46 | 116.27 ± 15.45 | 119.87 ± 16.08 | 123.68 ± 16.04 | < 0.001 |
| DBP (mmHg) | 69.95 ± 9.74 | 72.38 ± 10.19 | 74.73 ± 10.63 | 77.86 ± 10.83 | < 0.001 |
| BMI (kg/m2) | 21.22 ± 2.54 | 22.36 ± 2.88 | 23.62 ± 3.03 | 25.14 ± 2.99 | < 0.001 |
| AST | < 0.001 | ||||
| Low | 4655 (18.61%) | 3946 (15.77%) | 3247 (12.98%) | 1892 (7.56%) | |
| Medium | 3425 (13.69%) | 3700 (14.79%) | 3703 (14.80%) | 3148 (12.58%) | |
| High | 2233 (8.93%) | 3000 (11.99%) | 3859 (15.43%) | 5153 (20.60%) | |
| Not recorded | 14,704 (58.78%) | 14,370 (57.44%) | 14,207 (56.79%) | 14,827 (59.26%) | |
| ALT (U/L) | 13.7 (10.8, 18.4) | 15.9 (12.0, 22.3) | 19.0 (13.9, 27.2) | 25.4 (17.9, 37.9) | < 0.001 |
| HDL-C (mmol/L) | 1.62 ± 0.30 | 1.44 ± 0.24 | 1.32 ± 0.23 | 1.15 ± 0.23 | < 0.001 |
| TG (mmol/L) | 0.60 (0.50, 0.70) | 0.90 (0.79, 1.01) | 1.26 (1.10, 1.45) | 2.10 (1.71, 2.66) | < 0.001 |
| LDL-C (mmol/L) | 2.54 ± 0.59 | 2.68 ± 0.63 | 2.83 ± 0.67 | 2.94 ± 0.72 | |
| TC (mmol/L) | 4.53 ± 0.79 | 4.62 ± 0.83 | 4.79 ± 0.88 | 5.04 ± 0.92 | < 0.001 |
| BUN (mmol/L) | 4.55 ± 1.16 | 4.58 ± 1.18 | 4.67 ± 1.17 | 4.72 ± 1.12 | < 0.001 |
| Scr (umol/L) | 63.46 ± 13.61 | 68.28 ± 15.76 | 72.08 ± 15.84 | 75.44 ± 14.91 | |
| FPG (mmol/L) | 4.72 ± 0.46 | 4.78 ± 0.46 | 4.81 ± 0.48 | 4.85 ± 0.47 | < 0.001 |
| AIP | -0.44 ± 0.11 | -0.20 ± 0.05 | -0.01 ± 0.06 | 0.29 ± 0.15 | < 0.001 |
Values are n (%) or mean ± standard deviation
AIP: atherogenic index of plasma, SBP systolic blood pressure, DBP diastolic blood pressure, BMI body mass index, ALT alanine aminotransferase, AST aspartate aminotransferase, HDL-C high-density lipoprotein cholesterol, LDL-C low-density lipoprotein cholesterol, TC total cholesterol, TG triglycerides, Scr serum creatinine, BUN blood urea nitrogen, FPG fasting plasma glucose