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. Author manuscript; available in PMC: 2023 Aug 11.
Published in final edited form as: Antiviral Res. 2022 May 6;203:105330. doi: 10.1016/j.antiviral.2022.105330

Fig. 1.

Fig. 1.

FR-S, but not FR, inhibits DENV-2 and ZIKV replication. U937-DC-SIGN cells were infected with (A) DENV-2 (Nicaraguan strain 172–06) or (B) ZIKV (Nicaraguan strain 2–16) and treated simultaneously or 1 h post-infection with different concentrations of FR, FR-S, or the positive control celgosivir (CEG). Viral replication was quantified by flow cytometry with intracellular labeling of nonstructural protein 3 (NS3), indicating active replication. Mouse anti-NS3 Alexa Fluor 647 conjugated mAb (E1D8) was used for NS3 staining.