Skip to main content
. Author manuscript; available in PMC: 2023 Aug 11.
Published in final edited form as: J Alzheimers Dis. 2020;78(2):721–734. doi: 10.3233/JAD-200132

Figure 3:

Figure 3:

Lower baseline CMRgl in APOE4 carriers compared with APOE4 non-carriers

Statistical difference brain maps (uncorrected threshold of p=0.005) of the metabolic reduction between APOE4 carriers and non-carriers based on voxel-wise FDG analysis. As expected, compared with APOE4 non-carriers there is a reduction in CMRgl uptake in the APOE4 carriers. Colored areas indicate regions of lower CMRgl inAPOE4 carriers compared to non-carriers. See text for the global significance (p<0.001) based on the Monte Carlo simulation.