Table 1.

Ongoing clinical trials using body fluids for GBM detection and monitoring.

Study Title	Status	Biospecimen	Study Type and Time Frame	ClinicalTrials.gov Identifier
Unique Blood and CSF Metabolic Profile Association with Gliomas in Adults	Recruiting	Plasma CSF	Observational 10 years	NCT03865355
A Biospecimen Collection Study in BRAF-V600E Mutated Recurrent Gliomas	Recruiting	Blood CSF Tumor tissue	Observational Procedure: Surgical Cohort 6 years	NCT03593993
Testing Cerebrospinal Fluid for Cell-free Tumor DNA in Children, Adolescents, and Young Adults with Brain Tumors	Not Yet Recruiting	CSF Tumor tissue	Observational 5 years	NCT05934630
Evaluating the Role of Cerebrospinal Fluid (CSF) Cell-free DNA (cfDNA) as a Prognostic Biomarker in Glioblastoma	Recruiting	●CSF ○ctDNA	Observational Diagnostic Test: Lumber Puncture 5 years	NCT05927610
Longitudinal Assessment of Marrow and Blood in Patients with Glioblastoma	Not Yet Recruiting	Peripheral blood sample collection Tumor collection Bone marrow aspiration	Observational 1 year	NCT04657146
Sonobiopsy for Noninvasive and Sensitive Detection of Glioblastoma	Recruiting	●Blood ○ctDNA	Interventional 3 years	NCT05281731
Profiling Program of Cancer Patients with Sequential Tumor and Liquid Biopsies	Recruiting	Blood Tumor sample	Interventional Parallel Assignment 4 years	NCT05099068
Evaluating the Expression Levels of MicroRNA-10b in Patients with Gliomas	Recruiting	Blood Tumor tissue CSF	Observational 11 years	NCT01849952