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. 2023 Aug 5;12(15):2003. doi: 10.3390/cells12152003

Figure 3.

Figure 3

Representation of the effect of AQP3 and AQP7 inhibition with 200 nM of Z433927330 (iAQP3) and DFP00173 (iAQP7), respectively, and both AQGPs with phloretin (PHL) in sperm motility (A) and membrane glycerol permeability (exponential rate coefficient) (B) of spermatozoa from normozoospermic men. Effect of AQP7 inhibition in membrane glycerol permeability (C) and AQP7 expression levels (D) of sperm from normozoospermic versus asthenozoospermic men. Results presented in min. to max. graphs, with a cross representing the mean of the sample size. Significantly different results with p < 0.05 are indicated as: *; p < 0.01 are indicated as: **; and p < 0.001 are indicated as: ***. Graphical representation of the negative correlation between the effect of AQP7 inhibition on sperm glycerol permeability and the percentage of sperm motility (E). (A) n = 12; (B) n = 30; (C) n = 30; (D) n = 20; (E) n= 42.