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Tr-OxPLs cause more pronounced exacerbation of HKSA-induced barrier disruption in old mice lung EC. Lung ECs from young and old mice seeded on ECIS array plates were subjected to HKSA (30 min), followed by the addition of indicated Tr-OxPLs. TER was monitored, and normalized resistance was plotted against time. Comparative analysis of combined effects of HKSA and each Tr-OxPL on TER decline in lung ECs from young and old mice; n = 6.
