Inhibition of CD36 ameliorates Tr-OxPLs-induced lung injury in vivo. (A) Young and old mice received concurrent injection of L37pA (20 mg/kg, i.v.) and KOdiA-PC (10 mg/kg, i.v.). After 24 h, BAL was collected to determine total protein content, total cell counts and PMN counts; n = 6, * p < 0.05 vs. KOdiA-PC alone, ** p < 0.05 vs. young group. (B) Evans blue lung extravasation assay in KOdiA-PC-challenged mice. Shown are representative images of three independent experiments; n = 6 mice per condition. (C) Young and old CD36 knockout mice were exposed to KOdiA-PC; protein content, total cell and PMN counts were determined in BAL; n = 6, * p < 0.05 vs. young group; ** p < 0.05 vs. wild-type group; ND, no difference.