Figure 7.

Effects of juvenile chronic CBDV treatment on social interaction and acoustic startle response (Study 2). Time spent performing direct affiliative behaviors (including sniffing and contact) towards an unfamiliar adult NMRI female mouse was assessed during the first and second 3 min time bins of a 6 min interaction session (a). Body startle (ln-transformed to meet the normality assumptions of parametric ANOVA) was measured in response to acoustic stimuli of 6, 12, 18 and 24 dB over a background of 66 dB (b). Data are expressed as mean ± SEM. Numbers in histograms indicate sample size for each group. * p < 0.05 from post hoc comparisons following a significant interaction (a) or from separate ANOVAs in each treated group (b).