Table 3.
piRNAs content in EVs collected from different cancer types.
| Cancer Type | piRNA | EV Origin | Target/Role | References |
|---|---|---|---|---|
| Lung | piR-26925 piR-5444 piR-164586 |
Serum | Biomarker | [61,62] |
| Ovarian | piR-25783 | CM | TGF-β/SMAD2 /SMAD3 pathway |
[74] |
| Gastric | piR-019308 piR-004918 piR-018569 |
Serum | Biomarker | [64] |
| Prostate | piR-349843 piR-382289 piR-158533 piR-002468 |
Urine | Biomarker | [72] |
| Neuroblastoma | piR-1089 | Plasma | KEAP1 | [71] |
| Multiple Mieloma | piR-823 | CM, Plasma | IL-6, VEGF ICAM-1 |
[105] |
| Cholangio Gallbladder carcinoma | piR-2660989 piR-10506469 piR-20548188 piR-10822895 piR23209 piR-18044111 |
Plasma | Biomarker | [76] |
| Bladder | piR-5936 | Plasma | Biomarker | [73] |