Table 1.
Characteristics of cohort; BC=breast cancer, OC=ovarian cancer, and PV=pathogenic variant.
| Individuals | |
|---|---|
| n | 382 |
| Age | |
| Mean | 45 |
| Range | 18–69 |
| Healthy | 164 |
| Affected | 218 |
| Affected by BC | 186 |
| Affected by OC | 30 |
| Affected by BC + OC | 2 |
| Age of onset of disease BC | |
| Mean | 46 |
| Range | 27–67 |
| Age of onset of disease OC | |
| Mean | 54 |
| Range | 22–67 |
| Array | |
| Multigene panel | 273 |
| Performed for healthy probands | 67 |
| Detected PVs | 17 |
| Performed for affected probands | 206 |
| Detected PVs | 39 |
| Sanger + PRS only | 109 |
| Performed for healthy probands | 97 |
| Detected PVs | 44 |
| Performed for affected probands | 12 |
| Detected PVs | 9 |