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. 2023 Jul 26;12(15):1941. doi: 10.3390/cells12151941

Figure 2.

Figure 2

miRNA binding sites at the rs8720 and rs12587 variants of the KRAS gene and their function in tumor regulation. (*) miRNA has been experimentally validated; it was observed that hsa-miR-4328 regulates genes involved in various cellular signaling pathways, such as EFGR, RET/PTC, KRAS, C-JUN, AP1/SP1 in the MAPK pathway and the genes ET1 and PTEN in the PI3K-AKT signaling pathway.