Table 4.

KRAS gene variants (rs8720 and rs12587) and their association with the clinic–pathologic variant of the CRC group.

Variant	Genotype	Variable	OR	95%(CI)	p Value
rs8720	CC	I–II stage	1.58	(1.03–2.42)	0.044
	CC	≥50 years old and I–II stage	1.62	(1.01–2.61)	0.044
	TC	Rectal	1.7	(1.12–2.58)	0.014
	TC	Rectal and ≥50 years old	1.58	(1.01–2.5)	0.046
	TC	Rectal and III–IV stage	1.92	(1.14–3.2)	0.017
	TC	Rectal and Mod differentiate	1.92	(1.22–3.01)	0.006
rs12587	GG	I–II stage	2.18	(1.28–3.71)	0.004
	GG	Male and stage I–II	2.08	(1.11–3.8)	0.030
	TG	Non-chemotherapy response and III–IV stage	1.8	(1.12–2.92)	0.01

Bivariate analysis, OR (odds ratio), CI (confidence intervals, p value adjusted (significant < 0.05).