TABLE 4.
Multivariate logistic regression predictors of discordance.
| Variables | Odds Ratio | 95% CI | p value | |
|---|---|---|---|---|
| Period | ||||
| Post‐October 2015 vs. Pre‐October 2015 | 1.19 | 1.01 | 1.41 | 0.03 |
| Etiology | ||||
| ALD vs. HCV | 0.92 | 0.66 | 1.27 | 0.13 |
| Crypto vs. HCV | 1.16 | 0.71 | 1.89 | |
| HBV vs. HCV | 1.62 | 0.95 | 2.77 | |
| HCV_ALD vs. HCV | 0.92 | 0.72 | 1.17 | |
| NASH vs. HCV | 1.28 | 0.92 | 1.78 | |
| Age | 1.01 | 1.00 | 1.02 | 0.28 |
| Gender | ||||
| F vs. M | 0.71 | 0.60 | 0.85 | 0.0002 |
| Ethnicity | ||||
| Black vs. White | 1.00 | 0.79 | 1.26 | 0.35 |
| Hispanic vs. White | 0.96 | 0.79 | 1.18 | |
| Other vs. White | 0.76 | 0.56 | 1.03 | |
| Region | ||||
| Central vs. West | 0.85 | 0.68 | 1.06 | 0.08 |
| Northeast vs. West | 0.78 | 0.63 | 0.97 | |
| South vs. West | 0.71 | 0.57 | 0.87 | |
| Wait time in months | 1.00 | 1.00 | 1.00 | 0.15 |
| Allocation MELD | 1.00 | 0.97 | 1.02 | 0.73 |
| AFP | ||||
| 21–99 vs. < =20 | 1.48 | 1.25 | 1.77 | <0.0001 |
| 100–499 vs. < =20 | 1.58 | 1.23 | 2.05 | |
| > = 500 vs. < =20 | 2.89 | 1.75 | 4.75 | |
| BMI | 1.00 | 1.00 | 1.02 | 0.64 |
| Tumor location | ||||
| Left vs. both | 0.10 | 0.08 | 0.12 | <0.0001 |
| Right vs. both | 0.20 | 0.18 | 0.24 | |
| Max tumor size (cm) | ||||
| 1–2 vs. <1 | 0.87 | 0.71 | 1.05 | <0.0001 |
| 2–3.5 vs. <1 | 0.77 | 0.64 | 0.93 | |
| > = 3.5 vs. <1 | 1.55 | 1.17 | 2.07 | |
| Number of tumors | ||||
| 2 vs. 1 | 1.34 | 1.07 | 1.69 | 0.0004 |
| 3 vs. 1 | 1.83 | 1.30 | 2.59 | |
| Treatments (LRT) since listing | ||||
| 0 vs. >1 | 0.54 | 0.46 | 0.65 | <0.0001 |
| 1 vs. >1 | 0.54 | 0.42 | 0.71 | |
| Treatments (LRT) since last radiology | ||||
| 0 vs. > −1 | 0.63 | 0.36 | 1.12 | 0.12 |
| Thermal ablation | ||||
| No vs. yes | 0.81 | 0.38 | 1.74 | 0.59 |
| Chemoembolisation | ||||
| No vs. yes | 1.45 | 0.79 | 2.65 | 0.23 |
| HCV serostatus | ||||
| Positive vs. negative | 1.05 | 0.80 | 1.37 | 0.47 |
| Unknown/not disclosed vs. negative | 0.69 | 0.35 | 1.36 | |
| HBcAB | ||||
| Positive vs. negative | 1.17 | 1.00 | 1.37 | 0.14 |
| Unknown/not disclosed vs. negative | 1.10 | 0.68 | 1.76 | |
| HBsAg | ||||
| Positive vs. negative | 0.94 | 0.59 | 1.49 | 0.15 |
| Unknown/not disclosed vs. negative | 0.57 | 0.32 | 1.01 | |
| Imaging | ||||
| MRI vs. CT | 1.14 | 0.99 | 1.32 | 0.07 |
| Time from imaging to transplant (days) | 1.00 | 1.00 | 1.01 | 0.05 |
Significant p values are indicated in bold.
Abbreviations: AFP, alpha‐fetoprotein; ALD, Alcohol related liver diseases; BMI, body mass index; HBcAB, hepatitis B core antibody; HBsAg, hepatitis B surface antigen; HBV, hepatitis B virus; HCV, hepatitis C virus; LRT, locoregional treatment; NASH, nonalcoholic steatohepatitis.