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. 2023 Jun 23;48(9):768–774. doi: 10.1097/RLU.0000000000004752

TABLE 1.

Demographic and Clinical Features of the 19 Participants With SAPHO Syndrome

Demographic and Clinical Features (N = 19)
Age, mean ± SD, y 52.4 ± 8.6
Sex, male/female, n 4/15
Age at symptom onset, mean ± SD, y 49.6 ± 8.0
Age at osteoarticular symptoms onset, mean ± SD, y 50.5 ± 8.2
Age at skin lesion onset, mean ± SD, y 49.9 ± 8.1
Disease duration, mean ± SD, mo 29.4 ± 14.5
Osteoarticular symptoms, n (%)
 Anterior chest pain 19 (100)
 Spinal pain 2 (10.5)
 Sacroiliac pain 3 (15.8)
 Peripheral skeletal or joint pain 2 (10.5)
 Craniofacial pain 1 (5.3)
Skin manifestations, n (%)
 Palmoplantar pustulosis 7 (36.8)
 Severe acne 5 (26.3)
 Psoriasis vulgaris 2 (10.5)
Laboratory examinations
 ESR, mean ± SD, mm/h 41.1 ± 21.4
 hs-CRP, mean ± SD, mg/L 7.6 ± 5.2
 Elevated ESR, n (%) 13 (68.4)
 Elevated hs-CRP, n (%) 7 (36.8)
 ANA-positive, n (%) 6 (31.6)
 Rheumatoid factor–positive, n (%) 0
 HLA-B27–positive, n (%) 0