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. 2023 Jul 31;12(15):1973. doi: 10.3390/cells12151973

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© 2023 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Bioinformatics analysis of functions, pathways and proteins dysregulated following DCUN1D1 knockdown in PCa cells (a) Enriched functions dysregulated in DU145 cells expressing the DCUN1D1 shRNA. (b) Top 10 pathways dysregulated following DCUN1D1 knockdown in DU145 prostate cancer cells. The list of genes up- and downregulated in DU145 cells expressing the DCUN1D1 shRNA was imported into the Ingenuity Pathway Analysis tool and canonical pathways were determined. Output represents dysregulated functions or pathways expressed as −log (p-value). (c) Bar chart of Panther pathway output from DU145 cells expressing DCUN1D1 shRNA.