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CAF-derived IGFBP7 enhances the metastatic and stemness ability of GC. (A) IGFBP7 promotes GC migration and invasion ability. (B) IGFBP7 induces EMT in GC cells. (C) IGFBP7 enhances the clonogenicity of GC cells. (D) IGFBP7 promotes GC sphere-forming ability. CAF IGFBP7 overexpression CM (CAF-IGFBP7 CM). *: p < 0.05, **: p < 0.01, and ***: p < 0.001. Original western blots have been presented in File S1.
