Representative single-cell whole-genome copy number alterations of breast and prostate cancer patients. CNA profiles are displayed as ratio to median. Vim status, as determined by immunofluorescence, is annotated on top of heatmaps, where Vim− cells = light orange and Vim+ cells = dark orange. Copy number gains are defined as >1.25 above median, losses as <0.75 below median and copy number neutral between 0.75–1.25. Copy number gains = red, copy number loss = blue, copy number neutral = white. (A–F) Single-cell CNV heatmaps of breast cancer patients (BC 1–6). (G) Single-cell CNV heatmap of a prostate cancer patient (PC 2).