| AAV2 | adeno-associated virus 2 |
| AMBRA1 | autophagy and beclin 1 regulator 1 |
| ATAD3A | ATPase family AAA domain-containing 3A |
| ATG5 | autophagy-related 5 |
| ATG12 | autophagy-related 12 |
| ATP | adenosine triphosphate |
| BECN-1 | beclin-1 |
| BNIP3 | BCL2-interacting protein 3 |
| CAV1 | caveolin-1 |
| CAV2 | caveolin-2 |
| CoQ10 | coenzyme Q10 |
| DNM1L | dynamin 1-like |
| DOA | dominant optic atrophy |
| DRP1 | dynamin-related protein 1 |
| ER | endoplasmic reticulum |
| GCC | ganglion cell complex |
| GTP | guanosine triphosphate |
| GWAS | genome-wide association study |
| HK2 | hexokinase 2 |
| HTG | high-tension glaucoma |
| IMM | inner mitochondrial membrane |
| IOP | intraocular pressure |
| iPSC | induced pluripotent stem cells |
| KEAP1 | Kelch-like ECH-associated protein 1 |
| LC3 | microtubule-associated protein 1A/1B-light chain 3 |
| LIR | LC3-interacting region |
| MEFs | mouse embryonic fibroblasts |
| MFN1 | mitofusin 1 |
| MFN2 | mitofusin 2 |
| MLC2 | myosin light chain 2 |
| MPTP | mitochondrial permeability transition pore |
| mtDNA | mitochondrial DNA |
| mTOR | mammalian target of rapamycin |
| NAD+ | nicotinamide adenine dinucleotide |
| NDP52/CALCOCO2 | calcium-binding and coiled-coil domain 2 |
| NF-κB | nuclear factor kappa-light-chain-enhancer of activated B cells |
| NMDA | N-Methyl-D-aspartic acid |
| NRF2 | NF-E2-related factor 2 |
| NTG | normal-tension glaucoma |
| OAG | open-angle glaucoma |
| OCR | oxygen consumption rate |
| OMM | outer mitochondrial membrane |
| ON | optic nerve |
| ONH | optic nerve head |
| OPA1 | optic atrophy-1 |
| OPTN | optineurin |
| OXPHOS | oxidative phosphorylation |
| PACG | primary angle-closure glaucoma |
| PARKIN | Parkin RBR E3 ubiquitin protein ligase |
| PARL | presenilin-associated rhomboid-like |
| PINK1 | PTEN-induced kinase 1 |
| PMI | P62-mediated mitophagy inducer |
| POAG | primary open-angle glaucoma |
| RNFL | retinal nerve fiber layer |
| RGCs | retinal ganglion cells |
| ROCK1 | Rho-associated coiled-coil containing protein kinase 1 |
| ROS | reactive oxygen species |
| 6-OHDA | 6-hydroxydopamine |
| SNP | single-nucleotide polymorphism |
| SQSTM1/p62 | sequestosome-1 |
| TAX1BP1 | tax1-binding protein 1 |
| TBK1 | TANK-binding kinase 1 |
| TM | trabecular meshwork |
| TNFα | tumor necrosis factor alpha |
| TOMM20 | translocase of outer mitochondrial membrane 20 |
| TP53 | tumor protein p53 |
| UB | ubiquitin |
| UBAN | ubiquitin binding in ABIN and NEMO |
| UCP2 | uncoupling protein 2 |
| WDR36 | WD repeat domain 36 |