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[Preprint]. 2023 Aug 15:2023.07.31.551386. Originally published 2023 Aug 2. [Version 2] doi: 10.1101/2023.07.31.551386

PMC10418102.1; 2023 Aug 2
PMC10418102.2; 2023 Aug 15

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Figure 2. — (A) Venn diagram showing the number of significant LVs and their overlap across cell types and experimental conditions. (B) LV41 is deceased significantly in wild-type microglia during aging. (C) A heatmap showing significant LV-associated biological pathways or cell type markers. A linear model is used to test the effect of aging on each LV. P-values are adjusted for multiple comparisons using Benjamini-Hochberg method. A LV is differentially expressed if FDR < 0.05. LV: latent variable; AD, Alzheimer’s disease; WT, wild-type.