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[Preprint]. 2023 Aug 2:2023.08.02.551708. [Version 1] doi: 10.1101/2023.08.02.551708

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Fig 2 — A. baumannii genes and pathways that are vulnerable to knockdown. (A-B) Depletion of sgRNAs targeting transcription units (TUs) from the CRISPRi library during growth in inducer over two time points (T₁, and T₂). Vertical dashed lines indicate a two-fold loss in fitness relative to non-targeting sgRNAs and horizontal dashed lines indicate a Stouffer’s p value of ≤ 0.05. Stouffer’s p values were calculated at the TU level by combining the false discovery rates (FDRs) of all individual sgRNAs targeting the TU. TUs related to pathways discussed in the text are colored according to the figure legend and the number of essential genes in a TU is indicated by point size.