Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

[Preprint]. 2023 Aug 2:2023.08.02.551708. [Version 1] doi: 10.1101/2023.08.02.551708

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License, which allows reusers to copy and distribute the material in any medium or format in unadapted form only, for noncommercial purposes only, and only so long as attribution is given to the creator.

PMC Copyright notice

Fig 6 — Essential gene knockdown phenotypes in rifampicin (RIF) versus colistin (COL). Depletion of sgRNAs targeting transcription units (TUs) from the CRISPRi library during growth in inducer and RIF or COL at T₂. Vertical dashed lines indicate a two-fold loss in fitness relative to non-targeting sgRNAs and horizontal dashed lines indicate a Stouffer’s p value of ≤ 0.05. Stouffer’s p values were calculated at the TU level by combining the false discovery rates (FDRs) of all individual sgRNAs targeting the TU. TUs related to pathways discussed in the text are colored according to the figure legend and the number of essential genes in a TU is indicated by point size.