Fig. 4|.

Systematic benchmarking of cell type specific trans-regulatory potential performance. A, B. ROC curve and PR curve of trans-regulatory potential inference of STAT1 in classical monocytes. The ground truth of A to D is putative targets of TFs from ChIP-seq data for the corresponding cell types in PBMCs. C, D. Violin plot of AUC and AUPR ratio values of trans-regulatory potential performance across diverse TFs and cell types. E. Umap of PBMCs including 14 cell types. F. Umap of RUNX1 expression across PBMCs. G. Umap of cell level trans-regulatory potential for RUNX1(TF)-SPI1(TG) across PBMCs. H. Umap of cell level trans-regulatory potential for RUNX1(TF)-PRKCQ(TG) across PBMCs. I. Violin plot of cell level trans-regulatory potential from different cell types. This figure corresponds to the PBMCs.