Table 4.

Characteristics of infants with culture-confirmed EOS identified neither or only by the categorical approach.

ID	GA (w, d)	Max. Maternal Temp. (°C)	ROM (hrs)	GBS Status	Maternal Antibiotics	Infant Exam	Infant Culture Pathogen*	Probability of EOS	Calculator Recommendation
Identified by categorical approach only
1	37, 2	38.3	7.6	Neg	Broad >4hrs	Well	L. monocytogenes	0.22	Routine VS
2	39, 1	38.2	9.2	Pos	GBS IAP	Well	A. neurii (cord)	0.27	Routine VS
3	40, 6	38.1	3.3	Neg	None	Well	S. gallolyticus	0.30	Routine VS
4	39, 5	38.3	14.4	Pos	GBS IAP	Well	S. mitis (cord)	0.37	Routine VS
5	39, 0	38.1	14.3	Neg	None	Well	S. mitis	0.44	VS Q4hrs ×24h
6	39, 1	38.4	15.6	Pos	GBS IAP	Well	E. coli	0.45	VS Q4hrs ×24h
7	40, 2	38.1	17.1	Neg	None	Well	E. faecalis	0.48	VS Q4hrs ×24h
8	39, 6	38.0	26.7	Pos	None	Well	S. agalactiae	0.49	VS Q4hrs ×24h
9	41, 5	38.7	21.5	Neg	Broad >4hrs	Well	S. agalactiae (cord)	0.61	VS Q4hrs ×24h
10	39, 6	38.1	38.0	Neg	None	Well	S. viridans	0.68	VS Q4hrs ×24h
11	39, 1	39.1	24.0	Neg	Broad >4hrs	Well	S. anginosus (cord)	0.80	VS Q4hrs ×24h
12	35, 3	36.6	0.0	Pos	None	Equi.	S. viridans	0.98	Routine VS
Not identified by either approach
1	38, 3	37.4	11.9	Pos	GBS IAP	Well	S. aureus (csf)	0.09	Routine VS
2	41, 5	37.9	16.5	Neg	None	Well	S. aureus	0.51	VS Q4hrs ×24h
3	40, 6	37.2	0.8	Neg	None	Well	S. gallolyticus	0.05	Routine VS
4	40, 1	38.4	24.2	Neg	None	Well	E. coli	0.89	VS Q4hrs ×24h
5	39, 5	37.8	5.5	Neg	None	Well	E. coli	0.19	Routine VS

EOS: early onset sepsis; GA: gestational age; w: weeks; d: days; Max: maximum; Temp: temperature; ROM: rupture of membranes; hrs: hours; GBS:

Group B Streptococcus; Neg: Negative; Pos: Positive; Broad: broad spectrum antibiotics administered more than 4 hours before delivery; IAP:

intrapartum antibiotic prophylaxis; Equi: equivocal; csf: cerebral spinal fluid; VS: vital signs; Q4hrs × 24 hrs: every 4 hours for 24 hours.

^*Peripheral blood culture unless otherwise indicated in parentheses as cord blood or csf culture.