Table 1.
Clinical and biological characteristics of the study population.
| Control (n = 97) | DR (n = 97) | p Value | |
|---|---|---|---|
| Age (years) | 64.3 ± 8.7 | 64.4 ± 8.9 | 0.778 |
| Sex (M/F, %M) | 66/31 (68) | 66/31 (68) | >0.999 |
| Body mass index (kg/m2) | 29.8 [26.6;32.8] | 29.1 [26.3;34.1] | 0.553 |
| Diabetes duration (years) | 16.9 ± 9.3 | 16.9 ± 9.4 | >0.999 |
| Hypertension (n, %) | 80 (82) | 80 (82) | >0.999 |
| Dyslipidemia (n, %) | 67 (69) | 68 (70) | >0.999 |
| Nephropathy (n, %) | 36 (37) | 53 (55) | 0.021 |
| GFR (mL/min/1.73 m2) | 90 [73;103] | 82 [62;97] | <0.001 |
| HbA1c (%) | 7.8 [7.0;8.5] | 7.8 [7.0;8.6] | 0.824 |
| Cholesterol (g/L) | 1.61 [1.37;1.86] | 1.47 [1.23;1.76] | 0.051 |
| HDL-Chol (g/L) | 0.40 [0.34;0.48] | 0.43 [0.36;0.53] | 0.279 |
| LDL-Chol (g/L) | 0.87 [0.63;1.09] | 0.74 [0.57;1.01] | 0.172 |
| Triglycerides (g/L) | 1.40 [1.02;2.04] | 1.29 [0.79;1.77] | 0.099 |
| ASAT (UI/L) | 21 [18;28] | 23 [18;29] | 0.230 |
| ALAT (UI/L) | 24 [16;35] | 23 [17;31] | 0.240 |
| GGT (UI/L) | 29 [21;43] | 32 [21;64] | 0.109 |
Nephropathy: Urine albumin/creatinine ratio ≥ 30 mg/g or urine protein/creatinine ratio ≥ 300 mg/g or GFR ≤ 60 mL/min/1.73 m2; GFR: glomerular filtration rate; Chol: Cholesterol.