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. 2023 Aug 2;24(15):12350. doi: 10.3390/ijms241512350

Figure 2.

Figure 2

Kv7 current in Vdr/ pulmonary artery smooth muscle cells (PASMCs). (A,B) K+ current–voltage relationships measured before and after the addition of XE991 (10 µmol/L). Insets show representative current traces measured at +20 mV in the absence and presence of XE991 in (A) WT and (B) Vdr/ PASMCs. (C) XE991-sensitive current obtained by subtracting the K+ current in the presence of XE991 from the current in the absence of the drug. Insets show representative XE991-sensitive current traces measured at +20 mV. Results are means ± standard error of the mean (n = 4 animals and 8 cells per group). * p < 0.05, ** p < 0.01, *** p < 0.001 vs. WT using a two-way ANOVA test followed by a Bonferroni post hoc test.