Table 3.
Comparative values of COVID-19 characteristics of patients hospitalized with COVID-19 and vaccinated against SARS-CoV-2 compared to those hospitalized with COVID-19 and not vaccinated against SARS-CoV-2.
| Vaccinated Patients N = 129 (A) | Not Vaccinated Patients N = 172 (B) | p (t-Test) | |||||||
|---|---|---|---|---|---|---|---|---|---|
| Av. | SD | Min; Max | Median | Av. | SD | Min; Max | Median | ||
| Age (years old) |
61.8 | 16.8 | 18; 90 | 67 | 64 | 18.4 | 18; 96 | 68 | 0.28 |
| Hospitalization length (days) | 5.88 | 3.21 | 1; 19 | 5 | 6.75 | 3.60 | 1; 21 | 6 | 0.03 |
| Charlson score | 2.43 | 1.77 | 0; 7 | 3 | 2.66 | 1.78 | 0; 8 | 3 | 0.27 |
| Oxygen saturation at admission (%) | 94.75 | 3.73 | 60; 98 | 95 | 94.28 | 2.52 | 86; 98 | 95 | 0.19 |
| D-dimer (ng/mL) | 855.47 | 1264.90 | 130.6; 10,000 | 512.86 | 1390.02 | 1955.01 | 45; 12,226.32 | 798.27 | 0.01 |
| CK (U/L) | 181.04 | 324.08 | 14.2; 2477.2 | 86.8 | 363.8 | 2023.65 | 5.9; 25,125 | 97.5 | 0.33 |
| Troponin (ng/mL) | 36.72 | 228.09 | 1.5; 2171 | 4 | 64.01 | 294.6 | 1.5; 2947 | 5.8 | 0.45 |
| ESR (mm/1h) | 31.01 | 21.7 | 4; 90 | 24 | 36.12 | 23.71 | 2; 110 | 30 | 0.06 |
| C-reactive protein (mg/L) | 33.71 | 51.69 | 0.18; 378.09 | 11.85 | 39.94 | 51.17 | 0.18; 301.4 | 24.32 | 0.32 |
| Leukocytes (N/µL) | 7003.88 | 5420.67 | 1220; 47,000 | 6100 | 6449.71 | 6890.95 | 1020; 81,600 | 5400 | 0.45 |
| Platelets (N/µL) | 226,054.26 | 85,583.69 | 24,000; 683,000 | 213,000 | 205,575.58 | 82,571.96 | 36,000; 511,000 | 193,000 | 0.04 |
| Hb (g/dL) | 13.45 | 1.61 | 8.3; 17.2 | 13.6 | 13.1 | 1.74 | 7.5; 19.9 | 13.15 | 0.08 |
| ALT (U/L) | 30.61 | 24.87 | 7.2; 162.9 | 22.4 | 47.76 | 210.8 | 6.1; 2736.5 | 24.05 | 0.36 |
| AST (U/L) | 30.68 | 17.41 | 12.8; 130.8 | 24.6 | 52.4 | 132.17 | 10.5; 1578.4 | 29.95 | 0.07 |
| Total bilirubin (mg/dL) | 0.59 | 0.36 | 0.13; 2.74 | 0.52 | 0.74 | 1.32 | 0.15; 13.36 | 0.5 | 0.20 |
| Direct bilirubin (mg/dL) | 0.19 | 0.12 | 0.05; 0.74 | 0.16 | 0.34 | 1.16 | 0.04; 11.8 | 0.17 | 0.16 |
| Prothrombin concentration (%) | 95.72 | 18.61 | 28.5; 130 | 97.9 | 92.53 | 17.83 | 20.4; 129.5 | 96.2 | 0.15 |
| Serum urea (mg/dL) | 34.94 | 17.15 | 11.5; 116.4 | 30.3 | 36.75 | 20.22 | 8.3; 146.3 | 30.7 | 0.42 |
| Serum creatinine (mg/dL) | 1.03 | 0.5 | 0.52; 4.87 | 0.93 | 1.04 | 0.61 | 0.51; 7.25 | 0.9 | 0.93 |
| Serum glucose (mg/dL) | 106.26 | 27.69 | 26.2; 219.3 | 97.8 | 122.15 | 53.08 | 53.2; 357.7 | 105.65 | 0.01 |
| BMI | 27.328 | 6.302 | 17.04; 57.1 | 26.3 | |||||
| Number of days required for oxygen therapy | 0.52 | 1.89 | 0; 10 | 0 | 0.96 | 2.89 | 0; 19 | 0 | 0.13 |
| CURB 65 score | 1.51 | 0.64 | 0; 3 | 2 | 1.55 | 0.65 | 0; 3 | 2 | 0.64 |
Abbreviations and normal values: Av, Average; SD, Standard Deviation; Max, Maximum Value; Min, Minimum value; T-t, Student Test (t) for differences between means; Normal values: D-dimer < 500 ng/mL; CK, Creatine kinase 0–171 U/L; troponin 0.01–0.1 ng/mL; ESR, Erythrocytes sedimentation rate 0–15 mm/1 h; C-reactive protein < 10 mg/L; leukocytes 4000–10,000/µL; Hg, hemoglobin 13–17 g/dL; Platelets 150–450 × 106/µL; ALT, alanil-aminotransferase 0–45 U/L; AST, aspartate-aminotransferase 0/35 U/L; Total bilirubin 0.1–1.2 mg/dL; Direct bilirubin 0–0.2 mg/dL; Prothrombin concentration 70–100%;Serum urea 18–55 mg/dL; Serum creatinine 0.8–1.3 mg/dL; Serum glucose 74–108 mg/dL; BMI, body mass index 18.5–24.9 kg/m2.