FIG. 4.

Virion-associated Vpr stimulates HIV production during the early stage of infection. At each time interval after Jurkat T cells were infected with VSV-G-pseudotyped Vpr⁻, Vpr⁺ or Vpr⁺-T HIV (as indicated), supernatant from each infected culture was collected and the amount of virion-associated RT activity was determined. Values represent means of duplicate samples. Similar results were obtained in three independent experiments.