Skip to main content
PMC home page
The British Journal of Ophthalmology logoLink to The British Journal of Ophthalmology
. 1989 Nov;73(11):922–925. doi: 10.1136/bjo.73.11.922

Medical and surgical management of spontaneous hyphaema secondary to immune thrombocytopenia.

C J McDonald 1, A Raafat 1, M J Mills 1, J A Rumble 1
PMCID: PMC1041928  PMID: 2605148

Abstract

The medical and surgical management of an unusual case of spontaneous 'black ball' hyphaema complicated by secondary haemorrhage, raised intraocular pressure and corneal blood staining, and secondary to immune thrombocytopenia is presented. The literature is reviewed with particular reference to the aetiology and treatment of spontaneous hyphaema and the role of intravenous immunoglobulins in the preoperative management of patients with thrombocytopenia who present for routine or emergency ocular surgery.

Full text

PDF
922

Images in this article

923Image
on p.923
923Image
on p.923

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Ackerman J., Goldstein M., Kanarek I. Spontaneous massive vitreous hemorrhage secondary to thrombocytopenia. Ophthalmic Surg. 1980 Sep;11(9):636–637. [PubMed] [Google Scholar]
  2. Bartholomew R. S. Viscoelastic evacuation of traumatic hyphaema. Br J Ophthalmol. 1987 Jan;71(1):27–28. doi: 10.1136/bjo.71.1.27. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Clarkson S. B., Bussel J. B., Kimberly R. P., Valinsky J. E., Nachman R. L., Unkeless J. C. Treatment of refractory immune thrombocytopenic purpura with an anti-Fc gamma-receptor antibody. N Engl J Med. 1986 May 8;314(19):1236–1239. doi: 10.1056/NEJM198605083141907. [DOI] [PubMed] [Google Scholar]
  4. Diddie K. R., Dinsmore S., Murphree A. L. Total hyphema evacuation by vitrectomy instrumentation. Ophthalmology. 1981 Sep;88(9):917–921. doi: 10.1016/s0161-6420(81)80006-1. [DOI] [PubMed] [Google Scholar]
  5. Edwards W. C., Layden W. E. Monocular versus binocular patching in traumatic hyphema. Am J Ophthalmol. 1973 Sep;76(3):359–362. doi: 10.1016/0002-9394(73)90491-1. [DOI] [PubMed] [Google Scholar]
  6. Fraser D. J., Jr, Font R. L. Ocular inflammation and hemorrhage as initial manifestations of uveal malignant melanoma. Incidence and prognosis. Arch Ophthalmol. 1979 Jul;97(7):1311–1314. doi: 10.1001/archopht.1979.01020020053012. [DOI] [PubMed] [Google Scholar]
  7. Ganley J. P., Geiger J. M., Clement J. R., Rigby P. G., Levy G. J. Aspirin and recurrent hyphema after blunt ocular trauma. Am J Ophthalmol. 1983 Dec;96(6):797–801. doi: 10.1016/s0002-9394(14)71926-9. [DOI] [PubMed] [Google Scholar]
  8. HOWARD G. M. Spontaneous hyphema in infancy and childhood. Arch Ophthalmol. 1962 Nov;68:615–620. doi: 10.1001/archopht.1962.00960030619008. [DOI] [PubMed] [Google Scholar]
  9. Imbach P., Barandun S., d'Apuzzo V., Baumgartner C., Hirt A., Morell A., Rossi E., Schöni M., Vest M., Wagner H. P. High-dose intravenous gammaglobulin for idiopathic thrombocytopenic purpura in childhood. Lancet. 1981 Jun 6;1(8232):1228–1231. doi: 10.1016/s0140-6736(81)92400-4. [DOI] [PubMed] [Google Scholar]
  10. Imbach P., Wagner H. P., Berchtold W., Gaedicke G., Hirt A., Joller P., Mueller-Eckhardt C., Müller B., Rossi E., Barandun S. Intravenous immunoglobulin versus oral corticosteroids in acute immune thrombocytopenic purpura in childhood. Lancet. 1985 Aug 31;2(8453):464–468. doi: 10.1016/s0140-6736(85)90400-3. [DOI] [PubMed] [Google Scholar]
  11. Kageler W. V., Moake J. L., Garcia C. A. Spontaneous hyphema associated with ingestion of aspirin and ethanol. Am J Ophthalmol. 1976 Oct;82(4):631–634. doi: 10.1016/0002-9394(76)90553-5. [DOI] [PubMed] [Google Scholar]
  12. Kelman C. D., Brooks D. L. Ultrasonic emulsification and aspiration of traumatic hyphema. A preliminary report. Am J Ophthalmol. 1971 Jun;71(6):1289–1291. doi: 10.1016/0002-9394(71)90977-9. [DOI] [PubMed] [Google Scholar]
  13. Liesegang T. J. Clinical features and prognosis in Fuchs' uveitis syndrome. Arch Ophthalmol. 1982 Oct;100(10):1622–1626. doi: 10.1001/archopht.1982.01030040600009. [DOI] [PubMed] [Google Scholar]
  14. Magauran D. M. Unilateral spontaneous hyphaema. Br J Ophthalmol. 1973 Dec;57(12):945–947. doi: 10.1136/bjo.57.12.945. [DOI] [PMC free article] [PubMed] [Google Scholar]
  15. Newland A. C. Clinical use of intravenous immunoglobulin in blood disorders. Blood Rev. 1988 Sep;2(3):157–167. doi: 10.1016/0268-960x(88)90021-5. [DOI] [PubMed] [Google Scholar]
  16. Newland A. C., Treleaven J. G., Minchinton R. M., Waters A. H. High-dose intravenous IgG in adults with autoimmune thrombocytopenia. Lancet. 1983 Jan 15;1(8316):84–87. doi: 10.1016/s0140-6736(83)91738-5. [DOI] [PubMed] [Google Scholar]
  17. Ormerod L. D., Egan K. M. Spontaneous hyphaema and corneal haemorrhage as complications of microbial keratitis. Br J Ophthalmol. 1987 Dec;71(12):933–937. doi: 10.1136/bjo.71.12.933. [DOI] [PMC free article] [PubMed] [Google Scholar]
  18. Read J. Traumatic hyphema: surgical vs medical management. Ann Ophthalmol. 1975 May;7(5):659-62, 664-6, 668-70. [PubMed] [Google Scholar]
  19. Spoor T. C., Hammer M., Belloso H. Traumatic hyphema. Failure of steroids to alter its course: a double-blind prospective study. Arch Ophthalmol. 1980 Jan;98(1):116–119. doi: 10.1001/archopht.1980.01020030118011. [DOI] [PubMed] [Google Scholar]
  20. Wenske C., Gaedicke G., Küenzlen E., Heyes H., Mueller-Eckhardt C., Kleihauer E., Lauritzen C. Treatment of idiopathic thrombocytic purpura in pregnancy by high-dose intravenous immunoglobulin. Blut. 1983 Jun;46(6):347–353. doi: 10.1007/BF00320695. [DOI] [PubMed] [Google Scholar]

Articles from The British Journal of Ophthalmology are provided here courtesy of BMJ Publishing Group

RESOURCES