Figure 7.

FvWRKY50 is an important gene that regulates both vegetative growth and reproductive growth in strawberry. During vegetative growth, FvWRKY50 negatively regulates leaf senescence by directly targeting FvSAUR36. Then FvWRKY50 affects flowering time mainly by repression the expression of FvFT2, FvFT3, and FvCO. During the fruiting stages, complete mutation of FvWRKY50 leads to abnormal fertility of strawberry. High expression of FvWRKY50 can promote ripening and coloring of strawberry fruit. However, at low temperature FvWRKY50 is phosphorylated by FvMAPK3, and ubiquitination-mediated degradation of FvWRKY50 protein occurs, resulting in delayed fruit coloring. In conclusion, FvWRKY50 is a key gene in the regulation of strawberry growth and fruit ripening. It is of great value to continue to explore the regulatory mechanisms of FvWRKY50 in different biological processes of strawberry.