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. 2023 Apr 5;41(22):3805–3815. doi: 10.1200/JCO.22.01728

FIG 1.

FIG 1.

Enrollment, random assignment, and flow of study patients. N2 = ipsilateral mediastinal lymph node metastasis; N3 = contralateral lymph node metastasis; unforeseen N2 disease/uN2 = pathologically proven N2 disease at lymph node dissection at the time of tumor resection when previous mediastinal staging showed N0 or N1. aMain reasons for declining study entry were objection to clinical trials/randomization and preference for additional staging certainty with mediastinoscopy. bCervical radiation fibrosis from a previous nonpulmonary malignancy. cMediastinal radiation fibrosis from a previous nonpulmonary malignancy. SCLC, small-cell lung cancer.