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. 2023 Aug 5;24(15):12464. doi: 10.3390/ijms241512464

Table 1.

TLR2-dependent pro- and anti-inflammatory responses.

TLR Dimer Ligand Cytokines/Chemokines References
TLR2/1 Triacyl LPs
Pam3CSK4
IL-6, IL-8, TNF-α, IL-1α, IL-1β, IL-12, IL-13, IFN-α, IFN- β [12,102,103]
TLR2/6 Diacyl LPs
Pam2CSK4
FSL-1
IL-6, IL-8, IL-12, TNF-α, IFN-α, IFN- β, CXCL-10 [12,104,105]
TLR2/? Listeria monocytogenes IL-10 [101]
TLR2/? Bacteroides fragilis PSA IL-10, IFN-γ [89,90,91]
TLR2/? LPS TNF, CXCL10, IL10 [28]
TLR2/4 Hemoglobin, atypical LPS IL-12, IL-6, TNF-α [25]
TLR2/10 Helicobacter pylori TNF- α, IL-1β [56]