Table 1.
TLR Dimer | Ligand | Cytokines/Chemokines | References |
---|---|---|---|
TLR2/1 | Triacyl LPs Pam3CSK4 |
IL-6, IL-8, TNF-α, IL-1α, IL-1β, IL-12, IL-13, IFN-α, IFN- β | [12,102,103] |
TLR2/6 | Diacyl LPs Pam2CSK4 FSL-1 |
IL-6, IL-8, IL-12, TNF-α, IFN-α, IFN- β, CXCL-10 | [12,104,105] |
TLR2/? | Listeria monocytogenes | IL-10 | [101] |
TLR2/? | Bacteroides fragilis PSA | IL-10, IFN-γ | [89,90,91] |
TLR2/? | LPS | TNF, CXCL10, IL10 | [28] |
TLR2/4 | Hemoglobin, atypical LPS | IL-12, IL-6, TNF-α | [25] |
TLR2/10 | Helicobacter pylori | TNF- α, IL-1β | [56] |