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. 2023 Jul 26;28(15):5658. doi: 10.3390/molecules28155658

Figure 1.

Figure 1

The chemical structure and dose-response curve of ZINC15675948 determined by using the resazurin reduction assay. (A) 1,2,4-Oxadiazole nucleus. (B) Chemical structure of ZINC15675948. (C) Growth inhibition of ZINC15675948 toward leukemia CCRF-CEM and P-glycoprotein-overexpressing CEM/ADR5000 cell lines. (D) Growth inhibition of ZINC15675948 toward triple-negative breast cancer MDA-MB-231-pcDNA3 and BCRP overexpressing MDA-MB-BCRP cell lines. The data were plotted as mean ± SD from three independent experiments with each of the 6 parallel measurements.