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. 2023 Jul 26;28(15):5660. doi: 10.3390/molecules28155660

Figure 1.

Figure 1

Schematic diagram of a glioma-tailored NGS panel for detecting 1p/19q codeletion and driver gene mutations on a single platform. A patient with anaplastic oligodendroglioma with IDH-mutation and 1p/19q codeletion. For detection of 1p/19q codeletion, they analyzed copy number variations (CNVs) of chromosome 1p loci (9 genes), chromosome 1q loci (5 genes), chromosome 19p loci (5 genes), and chromosome 19q loci (5 genes). To validate 1p/19q codeletion detection, oligodendroglial tumor samples were tested by array-comparative genomic hybridization (CGH). Reprinted with permission from [7].