TABLE 4.

Nucleotide and amino acid changes associated with emergence of epizootic subtype IC VEE in 1992

Genome nucleotide no.	Gene and amino acid no.	Hypothetical ID progenitor	1992–1993 IC viruses	Amino acid change
161		T	C
464		G	A
543	nsP1, 167	A	G	N→D
1628	nsP1, 528	G	T	L→F
4665	nsP3, 212	C	T	H→Y
4667		C	T
5110	nsP3, 360	C	T	T→M
5768		C	T
6227		G	A
7217		C	A
7763	Capsid, 76	G	A	G→R
7810		T	C
8482		C	T
8680		T	A
9100		T	C
9116	E2, 193	G	A	G→R
9177	E2, 213	C	G	T→R
9259		T	C
9310		C	A
9872		T	C
9922		C	T
10216		C	T
10327		T	C
10438		G	A
11281		G	A