Table 6.

Results of the multivariate meta-analysis for the assay of malondialdehyde (MDA) and stratification according to different types of extract, disease, and tissue. Listed information includes differences between groups with the 95% confidence intervals.

	Difference	Coef.	p-Value	95% CI	# of Studies
Leaf Extract	control–case	−5.49	0.00	−7.15, 0.83	25
	stevia–case	−4.78	0.00	−6.37, −3.19	25
	stevia–control	0.71	0.00	0.24, 1.17	25
Aqueous	control–case	−3.85	0.00	−5.57, −2.14	8
	stevia–case	−3.3	0.00	−4.94, −1.65	8
	stevia–control	0.56	0.01	0.15, 0.96	8
Organic	control–case	−5.68	0.00	−8.97, −2.39	6
	stevia–case	−5.06	0.00	−6.82, −3.30	6
	stevia–control	0.62	0.48 a	−1.10, 2.34	6
Hydroalcoholic	control–case	−8.33	0.00	−14.08, −2.59	6
	stevia–case	−7.35	0.01	−13.01, −1.69	6
	stevia–control	0.98	0.01	0.25, 1.71	6
Diabetes melittus	control–case	−7.33	0.00	−12.25, 2.42	13
	stevia–case	−6.93	0.00	−11.73, −2.12	13
	stevia–control	0.41	0.12 a	−0.10, 0.92	13
Liver injury	control–case	−6.33	0.00	−10.04, −2.61	6
	stevia–case	−4.37	0.00	−6.61, −2.13	6
	stevia–control	1.95	0.02	0.35, 3.55	6
Renal disorder	control–case	−4.53	0.00	−5.77, −3.29	5
	stevia–case	−3.82	0.00	−5.11, −2.53	5
	stevia–control	0.71	0.01	0.17, 1.25	5
Blood	control–case	−1.81	0.15	−4.30, 0.67	2
	stevia–case	−1.32	0.19	−3.29, 0.64	2
	stevia–control	0.49	0.26 a	−0.36, 1.35	2
Liver	control–case	−6.96	0.00	−9.72, −4.19	11
	stevia–case	−5.91	0.00	−8.66, −3.16	11
	stevia–control	1.05	0.04	0.04, 2.05	11
Kidney	control–case	−3.13	0.00	−4.59, −1.66	4
	stevia–case	−2.45	0.00	−3.91, −0.99	4
	stevia–control	0.68	0.13 a	−0.21, 1.57	4
Intestine (duodenum–jejunum–ileum)	control–case	−4.99	0.00	−7.00, −2.98	3
	stevia–case	−4.64	0.00	−6.54, −2.74	3
	stevia–control	0.35	0.23 a	−0.23, 0.93	3
Pancreas	control–case	−3.91	0.02	−7.11, −0.71	2
	stevia–case	−3.89	0.01	−6.64, −1.13	2
	stevia–control	0.02	0.95 a	−0.81, 0.85	2

p-values with ^a represent non-statistically significant differences in MDA assay results; #: number of.