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Comparison of CD4+ T-cell responses in β2M−/− and B6 (β2M+/+) mice. (A) The mice were infected i.n. with 600 PFU of MHV-68, and spleen cells from individual animals were analyzed by flow cytometry at different time points as described for Fig. 2. The histograms represent the means ± SD for two to five animals, expressed as percent CD4+ T cells. (B) The total number of MHV-68-specific CD4+ T cells was determined as described for Fig. 3. The data points represent individual animals.
