T2DM	Type-2 diabetes mellitus
DPP-4	Dipeptidyl peptidase-4
SAR	Structure activity relationship
GLP-1	glucagon-like peptide-1
GIP	Glucose-dependent insulinotropic polypepide
DM	Diabetes mellitus
IC50	inhibitory concentration
cAMP	Cyclic adenosine monophosphate
BP	Blood pressure
GPCR	G-protein coupled receptors
MOE	Molecular operating environment
Nm	Nanomolar
NaH &MsCl	sodium hydride and methanesulfonyl chloride
MeCN	methyl cyanide
TEA	triethyl amine
EDC	1-ethyl-3-(3-dimethylaminopropyl)carbodiimide
PrOH	Propyl alcohol
FDA	Food and drug administration
H-bond & OH	Hydrogen bond and hydroxy
COOH	carboxlic acid
EDG withEWG	Electron donating group with Electron withdrawing groups
µM	Micro molar
HIV	Human immunodeficiency viruses
XP	Extra precision