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. 2023 Aug 11;9(32):eadg2699. doi: 10.1126/sciadv.adg2699

Fig. 1. DDM1 is a major restrictor for pericentromeric R-loop homeostasis.

Fig. 1.

(A) ssDRIP-seq data from different allelic mutants of ddm1. Mutant/wild-type (WT) values are plotted in 10-kb bins on chromosomes. Pericentromeric regions are shown as shaded area on each chromosome. (B) Snapshots of Integrative Genomics Viewer show R-loop levels (ssDRIP-seq) of ddm1 mutants in the chromosome 3 region: 13508431-13562105. “ddm1-1 + RNase H” was the control experiment for ddm1 ssDRIP-seq with commercial RNase H treatment before DRIP.