Table 4.
Risk of preterm birth stratified by active concurrent depression status among patients with post-traumatic stress disorder (PTSD) who gave birth between 2005 and 2015.
| Covariates | Crude ORsa for spontaneous preterm birth, no active depression (95% CI) N=1,250 |
Crude ORs for spontaneous preterm birth, with active depression (95% CI) N=1,922 |
|---|---|---|
| Preeclampsia/eclampsia | 2.41 (0.81-7.19) | 4.21 (1.76-10.10) |
| Number of antidepressant dispensations during pregnancyb | ||
| 0 | Ref | Ref |
| 1-2 | 1.53 (0.90-2.61) | 1.78 (1.14-2.78) |
| 3-5 | 1.37 (0.71-2.64) | 1.40 (0.87-2.27) |
| ≥6 | 3.21 (1.75-5.91) | 1.92 (1.17-3.13) |
a
Run as separate models for preeclampsia/eclampsia and number of antidepressant medication dispensations.
b
1 dispensation defined as number of fills of at least a 7-day supply of antidepressant prescription in the 12 months prior to childbirth.