Table 1.
The effect of cisplatin (2 mg/kg), A. muricata water extract (200 mg/kg), and A. muricata ethanol extract (200 mg/kg) on the pro-apoptotic and anti-apoptotic gene expression in tumor mass by using real-time PCR.
| Parameters | GII (EAC) |
GIII (EAC + Cisplatin) |
GIV (EAC + Water) |
GV (EAC + Ethanol) |
|---|---|---|---|---|
| BAX | 1.00 ± 0.58 | 6.51 ± 0.71 b | 2.19 ± 0.11 | 2.07 ± 0.21 |
| Bcl-2 | 1.00 ± 0.15 | 0.31 ± 0.09 b | 0.19 ± 0.05 b | 0.45 ± 0.13 b |
| Casp-3 | 1.00 ± 0.20 | 5.71 ± 1.88 b | 3.21 ± 1.40 | 2.13 ± 0.88 |
Results were expressed as mean ± SEM (n = 10). from the control group. p < 0.01 and b p < 0.001 from the EAC group. p < 0.001 from the EAC + Ethanol group. p < 0.001 from EAC + Water groups.