Table 4. Adverse events affecting >/= 5% of patients in either group.

CI: confidence interval; eGFR: estimated glomerular filtration rate

Adverse event	Risk ratio	95% CI	P value
Hyperkalemia	2.07	1.94-2.21	<0.00001
Nasopharyngitis	0.97	0.90-1.04	0.35
Hypertension	0.73	0.68-0.79	<0.00001
Anemia	1.07	0.99-1.17	0.10
Diarrhea	1.02	0.94-1.11	0.66
Upper respiratory tract infection	1.02	0.93-1.11	0.69
Decline in eGFR	1.30	1.15-1.47	<0.0001
Urinary tract infection	0.97	0.88-1.06	0.51
Back pain	1.01	0.93-1.10	0.74
Peripheral edema	0.65	0.60-0.70	<0.00001
Hypoglycemia	0.87	0.77-0.99	0.04
Dizziness	1.04	0.94-1.414	0.43
Arthralgia	1.06	0.97-1.15	0.17
Bronchitis	0.97	0.88-1.06	0.49
Constipation	0.91	0.80-1.03	0.14
Pneumonia	0.70	0.64-0.77	<0.00001