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. 2023 Aug 11;6:140. doi: 10.1038/s41746-023-00884-x

Table 2.

Univariate and multivariate linear mixed-effects models results.

Covariate Univariate Model Multivariate Model
β-coefficient [95% CI] β-coefficient [95% CI]
Physiological signals
Menstrual phase Late-follicular Reference Reference
Ovulation 0.06 [0.001, 0.12]* 0.08 [0.01, 0.15]*
Luteal 0.15 [0.09, 0.20]*** 0.16 [0.10, 0.22]***
Menstrual 0.09 [0.02, 0.16]** 0.03 [-0.04, 0.11]
Others Luteinizing Hormone (LH) –0.001 [-0.01, 0.003]
Estrogen (E3G) –0.0003 [–0.001, –0.00001]* –0.0003 [–0.001, –0.0001]**
Step Count –0.0003 [–0.0004, –0.0002]*** –0.0003 [–0.0004, –0.0002]***
Demographics
Age (yrs) 0.01 [–0.04, 0.05]
Height (cm) –0.01 [–0.04, 0.02]
Weight (kg) 0.002 [–0.01, 0.02]
BMI (kg/m²) 0.01 [–0.03, 0.05]
Self-reported experiences
Daily appetite Very low Reference Reference
Low –0.02 [–0.13, 0.10]
Moderate 0.04 [–0.08, 0.15]
High –0.01 [–0.13, 0.12]
Very high –0.02 [–0.20, 0.15]
Daily exercise Very low Reference Reference
Low –0.02 [–0.08, 0.05]
Moderate –0.02 [–0.09, 0.05]
High –0.08 [–0.17, 0.02]
Very high –0.05 [–0.24, 0.13]
Daily food cravings Did not experience Reference Reference
Very low 0.05 [–0.05, 0.14] 0.05 [–0.05, 0.15]
Low 0.15 [0.07, 0.24]*** 0.19 [0.10, 0.28]***
Moderate 0.19 [0.10, 0.28]*** 0.21 [0.12, 0.30]***
High 0.15 [0.06, 0.24]** 0.17 [0.07, 0.27]***
Very high 0.08 [–0.05, 0.20] 0.04 [–0.09, 0.17]
Daily bloating Did not experience Reference Reference
Very low –0.06 [–0.15, 0.03]
Low 0.02 [–0.06, 0.11]
Moderate 0.04 [–0.05, 0.13]
High 0.07 [–0.03, 0.17]
Very high –0.07 [–0.22, 0.08]
Daily fatigue Did not experience Reference Reference
Very low –0.14 [–0.26, −0.04]** –0.16 [–0.28, –0.03]*
Low 0.03 [–0.07, 0.14] 0.02 [–0.09, 0.13]
Moderate 0.01 [–0.09, 0.10] –0.03 [–0.13, 0.08]
High 0.03 [–0.07, 0.13] –0.03 [–0.14, 0.08]
Very high 0.08 [–0.03, 0.20] 0.03 [–0.10, 0.16]
Daily sleep issues Did not experience Reference Reference
Very low 0.001 [–0.10, 0.10] 0.05 [–0.06, 0.16]
Low –0.04 [–0.13, 0.06] –0.06 [–0.16, 0.05]
Moderate 0.04 [–0.06, 0.13] 0.02 [–0.09, 0.13]
High 0.11 [0.004, 0.22]* 0.05 [–0.07, 0.17]
Very high 0.09 [–0.03, 0.22] 0.02 [–0.12, 0.16]

The results of the univariate and multivariate linear mixed-effects models that were generated to estimate changes in median blood glucose across menstrual phases. Significant model results are indicated as such *p < 0.05, **p < 0.01, ***p < 0.001.