Table 1.
Statistical similarity analyses.
| MIMIC-III Dataset | ||||||||
|---|---|---|---|---|---|---|---|---|
| Feature type | Feature name | Original data | Synthetic data | KS-Stats | ||||
| Mean | Std | Miss rate (%) | Mean | Std | Miss rate (%) | |||
| Temporal | Heart rate | 82.56 | 17.34 | 36.53 | 82.20 | 15.91 | 35.74 | 0.01 |
| Respiratory rate | 18.85 | 5.31 | 37.88 | 18.29 | 4.54 | 36.72 | 0.04 | |
| calprevflg | 1.00 | 0.00 | 66.68 | 1.00 | 0.00 | 66.65 | 0.00 | |
| SpO2 | 97.30 | 3.38 | 67.99 | 97.39 | 2.27 | 67.39 | 0.03 | |
| O2 saturation pulse oximetry | 96.89 | 3.12 | 70.63 | 96.97 | 2.41 | 70.00 | 0.02 | |
| NBP [systolic] | 119.86 | 22.78 | 78.24 | 117.53 | 19.77 | 79.20 | 0.04 | |
| NBP [diastolic] | 56.64 | 14.75 | 78.26 | 56.89 | 13.20 | 79.29 | 0.03 | |
| NBP mean | 76.01 | 14.82 | 78.60 | 75.16 | 13.51 | 79.90 | 0.03 | |
| HR alarm [low] | 54.21 | 8.39 | 79.43 | 53.98 | 5.13 | 79.43 | 0.02 | |
| HR alarm [high] | 120.28 | 11.86 | 79.48 | 120.15 | 8.75 | 79.44 | 0.01 | |
| SpO2 alarm [low] | 89.73 | 8.77 | 33.76 | 89.54 | 9.43 | 33.61 | 0.02 | |
| SpO2 alarm [high] | 99.14 | 7.67 | 36.53 | 99.37 | 6.52 | 35.74 | 0.00 | |
| Resp alarm [high] | 32.77 | 8.14 | 37.88 | 32.17 | 5.34 | 36.72 | 0.03 | |
| Resp alarm [low] | 8.78 | 7.57 | 66.68 | 8.61 | 6.64 | 66.65 | 0.00 | |
| Previous weight (F) | 77.70 | 21.82 | 67.99 | 77.97 | 17.19 | 67.39 | 0.06 | |
| Static | Age | 91.33 | 67.41 | 0.00 | 93.05 | 70.15 | 0.00 | 0.02 |
| Gender | 0.51 | 0.49 | 0.00 | 0.52 | 0.49 | 0.00 | 0.00 | |
| Mortality | 0.10 | 0.30 | 0.00 | 0.09 | 0.29 | 0.00 | 0.01 | |
| eICU Dataset | ||||||||
|---|---|---|---|---|---|---|---|---|
| Feature type | Feature name | Original data | Synthetic data | KS-Stats | ||||
| Mean | Std | Miss rate (%) | Mean | Std | Miss rate (%) | |||
| Temporal | Noninvasive mean | 81.65 | 16.48 | 50.47 | 82.39 | 15.16 | 48.61 | 0.03 |
| Noninvasive systolic | 121.97 | 22.62 | 50.57 | 121.79 | 20.60 | 48.62 | 0.02 | |
| Noninvasive diastolic | 65.34 | 14.59 | 50.57 | 65.80 | 13.02 | 48.67 | 0.03 | |
| Bedside glucose | 150.86 | 59.10 | 81.44 | 149.28 | 49.85 | 84.62 | 0.04 | |
| Potassium | 3.98 | 0.55 | 91.02 | 3.92 | 0.48 | 91.98 | 0.04 | |
| Hgb | 10.35 | 2.14 | 91.98 | 10.47 | 2.10 | 92.17 | 0.04 | |
| Glucose | 130.45 | 48.72 | 91.98 | 132.15 | 47.56 | 92.26 | 0.03 | |
| Ssodium | 138.01 | 4.98 | 91.66 | 138.26 | 4.36 | 92.37 | 0.02 | |
| Creatinine | 1.35 | 1.20 | 92.07 | 1.34 | 1.11 | 92.42 | 0.01 | |
| Hct | 31.49 | 6.19 | 92.10 | 31.76 | 6.06 | 92.43 | 0.03 | |
| BUN | 24.37 | 17.55 | 92.12 | 23.23 | 16.67 | 92.89 | 0.04 | |
| Calcium | 8.42 | 0.71 | 92.43 | 8.39 | 0.70 | 92.66 | 0.03 | |
| Bicarbonate | 25.44 | 4.81 | 92.46 | 25.21 | 4.31 | 93.02 | 0.03 | |
| Platelets x 1000 | 215.19 | 104.12 | 92.74 | 207.75 | 94.41 | 93.30 | 0.02 | |
| WBC x 1000 | 10.39 | 4.83 | 92.81 | 10.00 | 4.16 | 93.53 | 0.02 | |
| Static | Age | 63.05 | 17.07 | 0.00 | 64.25 | 16.82 | 0.00 | 0.03 |
| Gender | 0.54 | 0.49 | 0.00 | 0.54 | 0.49 | 0.00 | 0.00 | |
| Mortality | 0.049 | 0.21 | 0.00 | 0.048 | 0.21 | 0.00 | 0.00 | |
Analyses on numerical temporal and static features of MIMIC-III and eICU data. KS-stats represent the maximum cumulative distribution function (CDF) difference between original and synthetic features (we ignore missing components when computing KS-stats).