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. 2023 Jul 8;129(4):672–682. doi: 10.1038/s41416-023-02338-3

Fig. 2. Genomic alterations of the cancer driver genes in metastatic gastric cancer by metastatic routes.

Fig. 2

Oncoprints of somatic mutations and copy number alterations are depicted for the primary and metastatic tumors of each patient with (a) hematogenous, (b) peritoneal, and (c) ovarian metastatic tumors. An asterisk indicates a de novo somatic mutation or gain/amplification in metastatic tumors. A diagonal line in a box indicates tumor hot spot mutations. (R175H of TP53 mutation in GCM15; Y42C and R5W of RHOA mutations in GCM09, GCM12 and GCM05, respectively).